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Sebastian Ewen Selected Research

Denervation

1/2022Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial.
1/2021Long-Term Results up to 12 Months After Catheter-Based Alcohol-Mediated Renal Denervation for Treatment of Resistant Hypertension.
1/2021Effect of Heart Rate on the Outcome of Renal Denervation in Patients With Uncontrolled Hypertension.
5/2020Effects of renal denervation on 24-h heart rate and heart rate variability in resistant hypertension.
1/2020The Current Status of Devices for the Treatment of Resistant Hypertension.
1/2020Alcohol-Mediated Renal Denervation Using the Peregrine System Infusion Catheter for Treatment of Hypertension.
1/2020Catheter-based renal denervation as adjunct to pulmonary vein isolation for treatment of atrial fibrillation: a systematic review and meta-analysis.
11/2018Renal Denervation Halts Left Ventricular Remodeling and Dysfunction in Heart Failure: New Shores Ahead.
8/2018Hypertension: history and development of established and novel treatments.
11/2017Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial.
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Sebastian Ewen Research Topics

Disease

48Hypertension (High Blood Pressure)
01/2022 - 05/2013
13Heart Failure
03/2022 - 05/2013
4Atrial Fibrillation
01/2021 - 10/2013
3Chronic Renal Insufficiency
07/2020 - 09/2013
3Fibrosis (Cirrhosis)
01/2018 - 05/2013
3Obstructive Sleep Apnea
01/2017 - 10/2013
3Cardiogenic Shock
01/2017 - 12/2014
3Sleep Apnea Syndromes (Sleep Apnea)
11/2014 - 08/2013
2Hemorrhage
01/2021 - 03/2014
2Cardiovascular Diseases (Cardiovascular Disease)
05/2020 - 04/2014
2Isolated Systolic Hypertension
01/2017 - 01/2015
2Inflammation (Inflammations)
01/2017 - 02/2015
2Myocardial Infarction
01/2017 - 12/2014
2Shock
01/2017 - 12/2014
2Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2017 - 04/2014
2Hypoxia (Hypoxemia)
08/2016 - 10/2013
2Systolic Heart Failure
02/2016 - 01/2016
1COVID-19
09/2022
1Cardiac Sudden Death (Sudden Cardiac Arrest)
03/2022
1Hypertensive Crisis
01/2021
1Infections
12/2020
1Aortic Valve Insufficiency (Aortic Regurgitation)
10/2020
1Coronary Artery Disease (Coronary Atherosclerosis)
10/2020
1unicuspid aortic valve
10/2020
1Thrombosis (Thrombus)
07/2020
1Non-ST Elevated Myocardial Infarction
04/2020
1Arteriovenous Fistula
01/2020
1Chronic Kidney Failure (Chronic Renal Failure)
01/2019
1Ventricular Remodeling
11/2018
1Fistula
08/2018
1Glucose Intolerance
07/2017
1Type 2 Diabetes Mellitus (MODY)
01/2017
1Ventricular Tachycardia
10/2016
1Hypersensitivity (Allergy)
09/2016
1Pheochromocytoma
04/2016
1Essential Hypertension
02/2015
1Hypertrophy
06/2014
1Albuminuria
05/2014
1Diabetes Mellitus
09/2013
1Metabolic Diseases (Metabolic Disease)
05/2013
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
05/2013
1Aortic Dissection
01/2013

Drug/Important Bio-Agent (IBA)

14Antihypertensive Agents (Antihypertensives)IBA
01/2021 - 08/2013
3Pharmaceutical PreparationsIBA
04/2020 - 11/2014
3Biomarkers (Surrogate Marker)IBA
08/2016 - 12/2014
3Glucose (Dextrose)FDA LinkGeneric
06/2014 - 05/2013
3DiureticsIBA
05/2014 - 08/2013
2C-Reactive ProteinIBA
09/2022 - 02/2015
2salicylhydroxamic acid (SHAM)IBA
01/2022 - 11/2017
2Paclitaxel (Taxol)FDA LinkGeneric
10/2020 - 04/2020
2omega-Chloroacetophenone (Mace)IBA
07/2020 - 05/2020
2Matrix Metalloproteinases (MMPs)IBA
01/2017 - 02/2015
2IvabradineIBA
02/2016 - 01/2016
2ReninIBA
12/2015 - 09/2013
2SodiumIBA
08/2015 - 09/2013
2Norepinephrine (Noradrenaline)FDA LinkGeneric
06/2014 - 05/2013
1TNF-Related Apoptosis-Inducing LigandIBA
09/2022
1Proteins (Proteins, Gene)FDA Link
09/2022
1Interferon-gamma (Interferon, gamma)IBA
09/2022
1PlasticsIBA
12/2020
1Polytetrafluoroethylene (Teflon)FDA Link
10/2020
1iopromide (Ultravist)FDA Link
04/2020
1MetalsIBA
04/2020
1mesoglycanIBA
01/2019
1Protein Isoforms (Isoforms)IBA
01/2018
1LigandsIBA
01/2018
1Angiotensin Receptors (Angiotensin II Receptor)IBA
07/2017
1Neprilysin (Neutral Endopeptidase)IBA
07/2017
1CH 66IBA
01/2017
1Receptor for Advanced Glycation End ProductsIBA
01/2017
1Anti-Arrhythmia AgentsIBA
10/2016
1Galectin 3 (LGALS3)IBA
08/2016
1pro-brain natriuretic peptide (1-76)IBA
08/2016
1AtropineFDA LinkGeneric
08/2016
1Atenolol (Tenormin)FDA LinkGeneric
08/2016
1AldosteroneIBA
12/2015
1Angiopoietin-2IBA
05/2015
1Interleukin-6 (Interleukin 6)IBA
02/2015
1Tissue Inhibitor of MetalloproteinasesIBA
02/2015
1Fibroblast Growth Factor-23IBA
12/2014
1Warfarin (Coumadin)FDA LinkGeneric
03/2014
1Vitamin KFDA Link
03/2014
1AnticoagulantsIBA
03/2014
1Oxidoreductases (Dehydrogenase)IBA
10/2013
1Connective Tissue Growth FactorIBA
10/2013
1NADP (NADPH)IBA
10/2013
1Adrenergic Agents (Adrenergic Drugs)IBA
05/2013

Therapy/Procedure

43Denervation
01/2022 - 01/2013
18Catheters
01/2021 - 05/2013
16Therapeutics
01/2020 - 05/2013
15Sympathectomy (Sympathectomies)
05/2020 - 05/2013
4Drug Therapy (Chemotherapy)
07/2017 - 05/2013
3Electrodes (Electrode)
01/2021 - 10/2016
2Polypharmacy
01/2021 - 07/2017
2Stents
07/2020 - 04/2020
1Defibrillators (Defibrillator)
03/2022
1Drug-Eluting Stents
04/2020
1Renal Dialysis (Hemodialysis)
01/2019
1Ligation
01/2019
1Extracorporeal Membrane Oxygenation
10/2015